Michael Brown, MD, will present a special lecture entitled “Fatricide: Murder by Fat” on Friday, August 2, at 1 pm in the Health Sciences Tower, Level 2, Lecture Hall 4. The lecture will be hosted by Kenneth Kaushansky, MD, Senior Vice President, Health Sciences and Dean, School of Medicine.
Michael S. Brown is the W.A. (Monty) Moncrief Distinguished Chair in Cholesterol and Arteriosclerosis Research, Regental Professor and Paul J. Thomas Chair in Medicine, UT Southwestern Medical Center. He received a BA degree in chemistry in 1962 and an MD degree in 1966 from the University of Pennsylvania. Dr. Brown was an intern and resident at the Massachusetts General Hospital and a postdoctoral fellow with Dr. Earl Stadtman at the National Institutes of Health. In 1971, he went to UT Southwestern where he rose through the ranks to become a professor in 1976. He is currently Paul J. Thomas Professor of Molecular Genetics and Director of the Jonsson Center for Molecular Genetics at UT Southwestern.
Dr. Brown and his long-time colleague, Dr. Joseph L. Goldstein, together discovered the low-density lipoprotein (LDL) receptor, which controls the level of cholesterol in blood and in cells. They showed that mutations in this receptor cause familial hypercholesterolemia, a disorder found in one of every 500 individuals worldwide that leads to premature heart disease. This discovery has led to development of the statins, one of the most frequently prescribed classes of medications in the developed world.
Dr. Brown has been one of the foremost advocates of the critical role that physician-scientists serve in advancing human health and furthering our understanding of the origins and treatment of human disease. He has received many awards for his work, including the U.S. National Medal of Science and the Nobel Prize for Medicine or Physiology.
This talk is designed for physicians, scientists and physician-scientists. A reception will follow the lecture.